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CD47 抗体

This anti-CD47 antibody is a 小鼠 单克隆 antibody detecting CD47 in FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1177375
发货至: 中国

Quick Overview for CD47 抗体 (ABIN1177375)

抗原

See all CD47 抗体
CD47

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD47 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

B6H12
  • 品牌

    BD Pharmingen™

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Lindberg, Lublin, Telen, Veile, Miller, Donis-Keller, Brown: "Rh-related antigen CD47 is the signal-transducer integrin-associated protein." in: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).

    Brown, Hooper, Ho, Gresham: "Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2785-94, (1991) (PubMed).

  • 抗原

    CD47

    别名

    CD47 (IAP)

    背景

    The B6H12 monoclonal antibody specifically binds to a 42-52 kDa N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. The B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells.
    Synonyms: IAP, CDw149, gp42, MER6, Neurophilin, OA3 , Rh-related antigen
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