PDCD1LG2 抗体
(5 references)Quick Overview for PDCD1LG2 抗体 (ABIN1177350)
抗原
See all PDCD1LG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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亚型
- IgG1 kappa
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anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-118) antibody
PDCD1LG2 适用: 人 WB, FACS, IHC, ELISA, IP, IF 宿主: 小鼠 Monoclonal 7F11D11 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 27-220) antibodyPDCD1LG2 适用: 人 WB, FACS, ELISA, IF, Coat 宿主: 小鼠 Monoclonal PDL2-2676 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 33-236) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 36-219) antibodyPDCD1LG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibodyPDCD1LG2 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal 24F-10C12 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibody (PE)PDCD1LG2 适用: 人 FACS 宿主: 小鼠 Monoclonal 24F-10C12 PE
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-268) antibodyPDCD1LG2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 22-111) antibodyPDCD1LG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D5 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 33-236) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 40-75), (N-Term) antibodyPDCD1LG2 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 2011CT786-31-38 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 8, pp. 2947-53, (2005) (PubMed).
: "Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 711-8, (2003) (PubMed).
: "Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 3, pp. 1257-66, (2003) (PubMed).
: "PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2." in: European journal of immunology, Vol. 32, Issue 3, pp. 634-43, (2002) (PubMed).
: "PD-L2 is a second ligand for PD-1 and inhibits T cell activation." in: Nature immunology, Vol. 2, Issue 3, pp. 261-8, (2001) (PubMed).
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: "Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 8, pp. 2947-53, (2005) (PubMed).
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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别名
- CD273
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背景
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The MIH18 monoclonal antibody specifically binds to CD273, the Programmed Death Ligand 2 (PD-L2). PD-L1 and PD-L2 are newly discovered members of the B7 family that are the ligands for the Programmed Death 1 (PD-1) receptor. They are expressed on immature dendritic cells and mature dendritic cells. PD-L1 is expressed on antigen-presenting cells, including IFN-g-stimulated monocytes and activated human and mouse dendritic cells. Monoclonal antibodies that block PD- 1 and PD-L2 on dendritic cells result in enhanced T cell proliferation and cytokine production. PD-L2, also called B7-DC, is expressed on placental trophoblasts, myocardial endothelium and medullary thymic epithelial cells. Studies show overlapping functions of PD-L1 and PD-L2 and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.
Synonyms: PDCD1LG2, PDCD1 ligand 2, PDCD1L2, PD-1 ligand 2, PD-L2, PDL2, B7-DC, Btdc
抗原
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