NCR1 抗体
(3 references)Quick Overview for NCR1 抗体 (ABIN1177346)
抗原
See all NCR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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亚型
- IgG1 kappa
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anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 198-206) antibody
NCR1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-258) antibodyNCR1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B11E12 unconjugated
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 17-258) antibodyNCR1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (Internal Region) antibodyNCR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 17-211) antibodyNCR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 121-230) antibodyNCR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) antibody (PE)NCR1 适用: Cow, Bison FACS 宿主: 小鼠 Monoclonal AKS1 PE
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-258) antibodyNCR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-255) antibodyNCR1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal n1D9 unconjugated
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应用备注
- This NA/LE™ format is useful for in vitro functional studies.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "NKp46." in: The international journal of biochemistry & cell biology, Vol. 33, Issue 12, pp. 1147-50, (2001) (PubMed).
: "NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against ..." in: European journal of immunology, Vol. 29, Issue 5, pp. 1656-66, (1999) (PubMed).
: "p46, a novel natural killer cell-specific surface molecule that mediates cell activation." in: The Journal of experimental medicine, Vol. 186, Issue 7, pp. 1129-36, (1997) (PubMed).
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: "NKp46." in: The international journal of biochemistry & cell biology, Vol. 33, Issue 12, pp. 1147-50, (2001) (PubMed).
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- NKp46
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背景
- NKp46, a major cytoxicity receptor of NK cells, is a type I membrane glycoprotein (46 kDa) is expressed on resting and activated NK cells. Its extracellular region contains two C2-type, Ig-like domains. The transmembrane domain contains a positively charged amino acid (Arg) which could be involved in stabilizing the association with CD3zeta. Its intracellular region does not contain immunoreceptor tyrosine-based activating motifs (ITAM), but it is linked to intracytoplasmic transduction machinery by its association with CD3zeta and FcepsilonRIgamma adaptor proteins. NKp46 along with NKp30 and NKp44 are referred to as natural cytoxicity receptors (NCR) and play a very important role in killing virus-infected, tumor cells and MHC-class I-unprotected cells. This antibody is routinely tested by flow cytometric analysis.
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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