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ITGA4 抗体

This anti-ITGA4 antibody is a 小鼠 单克隆 antibody detecting ITGA4 in FACS. Suitable for 人, Cow, 犬, 马, Cat, 绵羊, Cynomolgus, 猕猴 和 Baboon. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1177343
发货至: 中国

Quick Overview for ITGA4 抗体 (ABIN1177343)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

  • 137
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人, Cow, 犬, 马, Cat, 绵羊, Cynomolgus, 猕猴, Baboon

宿主

  • 76
  • 58
  • 27
小鼠

克隆类型

  • 100
  • 62
  • 2
单克隆

标记

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This ITGA4 antibody is un-conjugated

应用范围

  • 83
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Flow Cytometry (FACS)

克隆位点

9F10
  • 品牌

    BD Pharmingen™

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Berlin, Berg, Briskin, Andrew, Kilshaw, Holzmann, Weissman, Hamann, Butcher: "Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1." in: Cell, Vol. 74, Issue 1, pp. 185-95, (1993) (PubMed).

  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    CD49d

    背景

    The 9F10 monoclonal antibody specifically reacts with the integrin alpha4 chain, that is expressed as a heterodimer with either of two beta integrin subunits, beta1 (CD29) or beta7. The alpha4beta1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The alpha4beta7 integrin has a similar tissue distribution, except it is found on only a small subpopulation of thymocytes. Integrin alpha4beta7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression by and function of cells that express alpha4 chain-containing integrins.
    Synonyms: Integrin alpha4 chain, Integrin alpha 4, ITGA4, IA4, alpha 4 subunit of VLA-4

    途径

    Integrin Complex
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