No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
储存液
Azide free
储存条件
4 °C
储存方法
Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
抗原
ITGAL
(Integrin alpha-L (ITGAL))
别名
CD11a
背景
The HI111 monoclonal antibody specifically binds to the 180 kDa integrin alpha chain. This type I transmembrane glycoprotein associates with CD18 (integrin beta2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50). Synonyms: LFA-1alpha, Lymphocyte (Leukocyte) function-associated antigen 1 alpha chain, ITGAL