IL2RG 抗体
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北京 101111
Quick Overview for IL2RG 抗体 (ABIN1177316)
抗原
See all IL2RG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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Neutralization Activity: Neutralization activity may be measured with a proliferation assay using 60 pg/mL recombinant human IL-15 (Cat. No. 560254) to stimulate murine CTLL-2 cells at 2x10^4 cells/mL as indicator cells (i.e preincubation of the antibody with recombinant human IL-15 for 60 minutes).
50% Neutralization (ND50) at 0.02 - 3.0 µg/mL
> 85% Neutralization at 2-20 µg/mL -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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亚型
- IgG2a kappa
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anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 51-150) antibody
IL2RG 适用: 人, 大鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-262) antibodyIL2RG 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 4A8E5 unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-262) antibodyIL2RG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A8F2 unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 76-101), (N-Term) antibodyIL2RG 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB22117 unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-262) antibodyIL2RG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-263) antibodyIL2RG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) antibody (APC)IL2RG 适用: 人, 犬 FACS 宿主: 大鼠 Monoclonal TUGh4 APC
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-260) antibodyIL2RG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 75-230) antibodyIL2RG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, gamma (IL2RG) (N-Term) antibodyIL2RG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 1, pp. 9-12, (1995) (PubMed).
: "Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 4, pp. 1596-605, (1995) (PubMed).
: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, (1995) (PubMed).
: "Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes." in: Science (New York, N.Y.), Vol. 263, Issue 5152, pp. 1453-4, (1994) (PubMed).
: "Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4." in: Science (New York, N.Y.), Vol. 262, Issue 5141, pp. 1874-7, (1994) (PubMed).
: "T cell growth factor: parameters of production and a quantitative microassay for activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 120, Issue 6, pp. 2027-32, (1978) (PubMed).
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: "The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 1, pp. 9-12, (1995) (PubMed).
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- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
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别名
- CD132
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背景
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The 4G3 antibody reacts with the common gamma subunit (gammac) shared by the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors also known as CD132. This receptor is expressed constitutively at low levels on most lymphocytes, myeloid cells, embryonic thymocytes and lymphoid cell lines, but not non-lymphoid cells. The gammac receptor is a 75 - 80 kD transmembrane glycoprotein which mediates signal transducing activities of cytokine receptor complexes with which it is associated.
Synonyms: Common gamma chain, gammac -
途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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