电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IL-10RA 抗体

This anti-IL-10RA antibody is a 大鼠 单克隆 antibody detecting IL-10RA in FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1177308
发货至: 中国

Quick Overview for IL-10RA 抗体 (ABIN1177308)

抗原

See all IL-10RA (IL10RA) 抗体
IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

适用

  • 81
  • 51
  • 20
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1

宿主

  • 77
  • 22
  • 13
  • 2
大鼠

克隆类型

  • 77
  • 35
  • 1
单克隆

标记

  • 65
  • 10
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-10RA antibody is un-conjugated

应用范围

  • 77
  • 34
  • 28
  • 20
  • 15
  • 14
  • 11
  • 10
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

3F9
  • 品牌

    BD Pharmingen™

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

    亚型

    IgG2a kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Liu, de Waal Malefyt, Briere, Parham, Bridon, Banchereau, Moore, Xu: "The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 604-13, (1997) (PubMed).

    Carson, Lindemann, Baiocchi, Linett, Tan, Chou, Narula, Caligiuri: "The functional characterization of interleukin-10 receptor expression on human natural killer cells." in: Blood, Vol. 85, Issue 12, pp. 3577-85, (1995) (PubMed).

  • 抗原

    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

    别名

    CD210

    背景

    Reacts with 90-110 kDa protein expressed on T cells, B cells, NK cells, and monocyte/macrophages. It belongs to the class II cytokine receptor family which includes IFNgammaR (CDw119), IFNalpha/betaR (CD118) and tissue factor (CD142). IL-10R has been found to play a role in signal transduction by activating specific STAT proteins (STAT3 and STAT1) and inducing gene transcription. Other reports indicate that IL-10 protein binding to NK cells appears to be stimulatory, in contrast to its binding to T cells and monocytes/macrophages. Clone 3F9 is specific for human IL-10R and its binding to the receptor can be blocked by recombinant human IL-10 (rhIL-10).
    Synonyms: IL-10 receptor

    途径

    Growth Factor Binding
You are here:
Chat with us!