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Integrin alpha 1 抗体

Cited in 3+ publications. This anti-Integrin alpha 1 antibody is a Armenian Hamster 单克隆 antibody detecting Integrin alpha 1 in WB, IP, FACS, IHC (fro), BR 和 IHC (f). Suitable for 小鼠 和 大鼠.
产品编号 ABIN1177273
发货至: 中国
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中国
北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Integrin alpha 1 抗体 (ABIN1177273)

抗原

See all Integrin alpha 1 (ITGA1) 抗体
Integrin alpha 1 (ITGA1)

适用

  • 78
  • 25
  • 12
  • 4
  • 2
小鼠, 大鼠

宿主

  • 59
  • 23
  • 1
  • 1
  • 1
Armenian Hamster

克隆类型

  • 64
  • 21
单克隆

标记

  • 42
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin alpha 1 antibody is un-conjugated

应用范围

  • 51
  • 27
  • 25
  • 20
  • 16
  • 13
  • 13
  • 9
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

Ha31-8
  • 纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

    免疫原

    Rat Emulsified Lewis Rat Glomeruli Cells

    亚型

    IgG2 lambda
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Mendrick, Kelly, duMont, Sandstrom: "Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 72, Issue 3, pp. 367-75, (1995) (PubMed).

    Miyake, Sakurai, Okumura, Yagita: "Identification of collagen and laminin receptor integrins on murine T lymphocytes." in: European journal of immunology, Vol. 24, Issue 9, pp. 2000-5, (1994) (PubMed).

    Hemler: "VLA proteins in the integrin family: structures, functions, and their role on leukocytes." in: Annual review of immunology, Vol. 8, pp. 365-400, (1990) (PubMed).

  • 抗原

    Integrin alpha 1 (ITGA1)

    别名

    CD49a

    背景

    The Ha31/8 antibody reacts with the 180-kDa integrin alpha1 chain (CD49a), which is a transmembrane glycoprotein that non-covalently associates with the integrin beta1 subunit (CD29) to form the alpha1beta1 (complex known as VLA-1). VLA-1 has been reported to be expressed on activated T cells, monocytes, smooth muscle cells, and endothelial cells. It is a receptor for collagen and laminin. The Ha31/8 monoclonal antibody is specific for both rat and mouse CD49a. It has been reported that Ha31/8 antibody can block VLA-1-mediated binding of rat cells to collagen.
    Synonyms: Integrin alpha1 chain

    途径

    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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