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Ezrin 抗体 (pTyr353) (Alexa Fluor 488)

Name: Ezrin 抗体 (pTyr353) (Alexa Fluor 488)
SKU: ABIN1177059
Availability: OutOfStock

This anti-Ezrin antibody is a 小鼠单克隆 antibody detecting Ezrin in ICS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

(2 references)

产品编号 ABIN1177059

发货至: 中国

Quick Overview for Ezrin 抗体 (pTyr353) (Alexa Fluor 488) (ABIN1177059)

抗原

See all Ezrin (EZR) 抗体

Ezrin (EZR)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Ezrin antibody is conjugated to Alexa Fluor 488

应用范围

Intracellular Staining (ICS)

克隆位点

I66-386

Discover our top product EZR Primary Antibody

抗原表位
28

16

9

9

9

9

6

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5

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3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr353

品牌

BD Phosflow™

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Phosphorylated Human Ezrin Peptide

亚型

IgG1 kappa
anti-Ezrin (EZR) (AA 292-464) antibody
EZR 适用: 人, 小鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F1A9 unconjugated

anti-Ezrin (EZR) (AA 1-295) antibody
EZR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-586) antibody
EZR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (pTyr478) antibody
EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-586) antibody
EZR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1E11 unconjugated

anti-Ezrin (EZR) antibody
EZR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-Ezrin-1 unconjugated

anti-Ezrin (EZR) (pTyr353) antibody
EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 350-470) antibody
EZR 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 455-586) antibody
EZR 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-251) antibody
EZR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

样本量

20 μL

限制

仅限研究用
状态

Liquid

缓冲液

Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

The antibody was conjugated to Alexa Fluor® 488 under optimum conditions, and unreacted Alexa Fluor® 488 was removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Gautreau, Poullet, Louvard, Arpin: "Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 13, pp. 7300-5, (1999) (PubMed).

Krieg, Hunter: "Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin." in: The Journal of biological chemistry, Vol. 267, Issue 27, pp. 19258-65, (1992) (PubMed).
抗原

Ezrin (EZR)

别名

Ezrin

背景

Ezrin is a member of the ERM (ezrin-radixin-moesin) family of proteins that function as crosslinkers between the actin cytoskeleton and the plasma membrane. Ezrin is a substrate for the tyrosine kinase epidermal (EGF) and hepatocyte growth factor (HGF) receptors. Upon EGF or HGF stimulation, ezrin is phosphorylated on tyrosine 353 (Y353), which is required for its interaction with phosphatidylinositol 3 kinase p85 subunit and activation of Akt. The I66-386 monoclonal antibody recognizes the phosphorylated Y353 of human ezrin.

途径

Maintenance of Protein Location