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Ezrin 抗体 (pTyr353) (Alexa Fluor 488)

Name: Ezrin 抗体 (pTyr353) (Alexa Fluor 488)
SKU: ABIN1177059
Availability: OutOfStock

EZR 适用: 人 ICS 宿主: 小鼠 Monoclonal I66-386 Alexa Fluor 488

(2 references)

产品编号 ABIN1177059

发货至: 中国

Datasheet as PDF

抗原 See all Ezrin (EZR) 抗体

Ezrin (EZR)
抗原表位
28

16

9

9

9

9

6

6

5

5

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr353
适用
142

79

71

8

7

6

5

4

3

3

3

1

1

1

1
人
宿主
132

9

3

2
小鼠
Compatible Secondaries
克隆类型
126

19
单克隆
标记
92

6

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1
This Ezrin antibody is conjugated to Alexa Fluor 488
应用范围
119

57

29

17

16

13

13

13

10

8

3

2

1

1

1

1

1

1

1

1
Intracellular Staining (ICS)

品牌

BD Phosflow™

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Phosphorylated Human Ezrin Peptide

克隆位点

I66-386

亚型

IgG1 kappa

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anti-Ezrin (EZR) (pTyr353) antibody
EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

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EZR 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 455-586) antibody
EZR 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-251) antibody
EZR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

样本量

20 μL

限制

仅限研究用
状态

Liquid

缓冲液

Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

The antibody was conjugated to Alexa Fluor® 488 under optimum conditions, and unreacted Alexa Fluor® 488 was removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Gautreau, Poullet, Louvard, Arpin: "Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 13, pp. 7300-5, (1999) (PubMed).

Krieg, Hunter: "Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin." in: The Journal of biological chemistry, Vol. 267, Issue 27, pp. 19258-65, (1992) (PubMed).
抗原

Ezrin (EZR)

别名

Ezrin (EZR 产品)

背景

Ezrin is a member of the ERM (ezrin-radixin-moesin) family of proteins that function as crosslinkers between the actin cytoskeleton and the plasma membrane. Ezrin is a substrate for the tyrosine kinase epidermal (EGF) and hepatocyte growth factor (HGF) receptors. Upon EGF or HGF stimulation, ezrin is phosphorylated on tyrosine 353 (Y353), which is required for its interaction with phosphatidylinositol 3 kinase p85 subunit and activation of Akt. The I66-386 monoclonal antibody recognizes the phosphorylated Y353 of human ezrin.

途径

Maintenance of Protein Location