CD48 抗体
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北京 101111
Quick Overview for CD48 抗体 (ABIN1177003)
抗原
See all CD48 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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免疫原
- Mouse T lymphoma MBL-2
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亚型
- IgG1 lambda
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anti-CD48 (CD48) antibody (Biotin)
CD48 适用: 人, Non-Human Primate FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-102 Biotin
anti-CD48 (CD48) antibodyCD48 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-CD48 (CD48) (AA 27-220) antibodyCD48 适用: 人 FACS, WB, ELISA, IF 宿主: 小鼠 Monoclonal 6F9H2 unconjugated
anti-CD48 (CD48) antibodyCD48 适用: 人, Non-Human Primate FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-102 unconjugated
anti-CD48 (CD48) antibody (FITC)CD48 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-102 FITC
anti-CD48 (CD48) (AA 1-243) antibodyCD48 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD48 (CD48) (AA 1-169) antibodyCD48 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B8-2C2 unconjugated
anti-CD48 (CD48) (AA 27-220) antibodyCD48 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM43 unconjugated Recombinant Antibody
anti-CD48 (CD48) antibody (APC)CD48 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-102 APC
anti-CD48 (CD48) antibody (PE)CD48 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-102 PE
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Identification of the 2B4 molecule as a counter-receptor for CD48." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 11, pp. 5809-12, (1998) (PubMed).
: "Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival." in: The Journal of experimental medicine, Vol. 179, Issue 1, pp. 341-6, (1994) (PubMed).
: "CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1241-9, (1992) (PubMed).
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: "Identification of the 2B4 molecule as a counter-receptor for CD48." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 11, pp. 5809-12, (1998) (PubMed).
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- CD48
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别名
- CD48 (BCM1)
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背景
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The HM48-1 monoclonal antibody specifically binds to CD48 (previously known as BCM1 in mice, Blast-1 in human, and OX-45 in the rat), a GPI-anchored member of the Ig superfamily. It is widely distributed on leukocytes, but not on non-hematopoietic cells, and its ligands include CD2 (LFA-2) and CD244 (2B4 antigen). The HM48-1 mAb blocks binding of soluble CD2 to CD48-bearing cells, blocks the interaction of CD2 and CD244, inhibits spleen cell proliferative responses to mitogens, augments the proliferative response of spleen cells when cross-linked with anti-CD3e mAbs, and inhibits priming of CTL in vitro. In vivo administration of HM48-1 antibody can prolong survival of cardiac allografts, an effect which is greatly enhanced by the addition of anti-CD2 mAb 12-15. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes.
Synonyms: BLAST, BLAST-1, BCM1, HM48-1, MEM-102, Sgp-60, SLAMF2
抗原
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