(9 references)-
- 抗原 See all CD1d (CD1D) 抗体
- CD1d (CD1D) (CD1d Molecule (CD1D))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD1d antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
- 品牌
- BD Pharmingen™
- 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- 免疫原
- Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma and mouse L929 cells
- 克隆位点
- 1B1
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product CD1D Primary Antibody
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anti-CD1d Molecule (CD1D) (AA 56-271) antibody
CD1D 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) (AA 32-302) antibodyCD1D 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibodyCD1D 适用: 小鼠, 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibody (PE)CD1D 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 51-1 PE
anti-CD1d Molecule (CD1D) (AA 20-190) antibodyCD1D 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibodyCD1D 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) (AA 1-335) antibodyCD1D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) (Internal Region) antibodyCD1D 适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibodyCD1D 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 51-1 unconjugated
anti-CD1d Molecule (CD1D) (AA 64-298) antibodyCD1D 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Reported applications include immunoprecipitation, blocking of in vitro antigen-mediated stimulation of NK1+T cells, blocking of in vitro responses of some T cells to CD1d1, (possibly to the beta2m-associated form of CD1d, but not to beta2m-independent CD1d4), and in vivo inhibition of TGF-beta2 production. mAb 3C11 (Cat. no. 559871) has been reported to inhibit responses of some T cells to both beta2m-associated and beta2m-independent forms of CD1d.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids." in: Annual review of immunology, Vol. 17, pp. 297-329, (1999) (PubMed).
: "CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells." in: Science (New York, N.Y.), Vol. 283, Issue 5399, pp. 225-9, (1999) (PubMed).
: "Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-beta 2 and Th1 cytokines and ameliorates listeriosis in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 6955-8, (1999) (PubMed).
: "CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: beta 2-microglobulin-dependent and independent forms." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 4, pp. 1710-7, (1998) (PubMed).
: "CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 7, pp. 3121-7, (1998) (PubMed).
: "Mouse CD1 is mainly expressed on hemopoietic-derived cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 3, pp. 1216-24, (1997) (PubMed).
: "CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides." in: Science (New York, N.Y.), Vol. 278, Issue 5343, pp. 1626-9, (1997) (PubMed).
: "TAP-independent selection of CD8+ intestinal intraepithelial lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 11, pp. 4209-16, (1996) (PubMed).
: "Expression of murine CD1 on gastrointestinal epithelium." in: Science (New York, N.Y.), Vol. 250, Issue 4981, pp. 679-82, (1990) (PubMed).
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: "The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids." in: Annual review of immunology, Vol. 17, pp. 297-329, (1999) (PubMed).
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- 抗原
- CD1d (CD1D) (CD1d Molecule (CD1D))
- 别名
- CD1d (CD1D 产品)
- 别名
- CD1A antibody, R3 antibody, CD1D antibody, CD1D1 antibody, CD1d molecule antibody, CD1D antigen, d polypeptide antibody, CD1D antibody
- 背景
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The 1B1 antibody reacts with CD1d, a 48-kDa glycoprotein with structural homology to the major histocompatibility complex (MHC) class I molecules. The structure, expression, and functions of CD1 antigens are complex and have been reviewed. mAb 1B1 detects CD1d at varying levels on most types of bone marrow and peripheral leukocytes and on epithelial, dendritic, and lymphoid cells in the thymus. It appears to recognize CD1d only in association with beta2m. CD1d has been reported to be expressed by gastrointestinal tract epithelium and in the cytoplasm of hepatocytes as detected via immunohistochemical staining of frozen sections with mAb 3C11 (Cat. No. 559871, for the purified antibody), suggesting a possible role for CD1d in mucosal immunity. However, CD1d expression was not detectable, via flow cytometry, on intestinal epithelial cells in studies using the anti-CD1d mAbs 3C11, 1B1, and 9C7. The 1B1 antibody competes with mAb 3C11 in binding to mouse splenocytes.
Synonyms: CD1.1, Ly-38 - 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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