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CD16 抗体

CD16 适用: 人 FACS 宿主: 小鼠 Monoclonal 3G8 unconjugated
产品编号 ABIN1176930
发货至: 中国
  • 抗原 See all CD16 抗体
    CD16
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD16 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    免疫原
    Human polymorphonuclear leukocytes
    克隆位点
    3G8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD16 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Wirthmueller, Kurosaki, Murakami, Ravetch: "Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain." in: The Journal of experimental medicine, Vol. 175, Issue 5, pp. 1381-90, (1992) (PubMed).

  • 抗原
    CD16
    别名
    CD16 (CD16 产品)
    背景
    The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcgammaRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
    Synonyms: FcRIII, Fc-gamma RIII, FCG3, FCGR3, FCGRIII, FcgammaRIII, IGFR3
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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