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IL-2 抗体

IL2 适用: 人 ELISA, Neut, ICS 宿主: 大鼠 Monoclonal MQ1-17H12 unconjugated
产品编号 ABIN1176901
发货至: 中国
  • 抗原 See all IL-2 (IL2) 抗体
    IL-2 (IL2) (Interleukin 2 (IL2))
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    大鼠
    克隆类型
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    This IL-2 antibody is un-conjugated
    应用范围
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    ELISA, Neutralization (Neut), Intracellular Staining (ICS)
    品牌
    BD Pharmingen™
    产品特性
    Neutralization Activity: This antibody has been reported to be useful for the neutralization of recombinant human IL-2. Neutralization activity may be measured with a proliferation assay using 100 pg/mL recombinant human IL-2 (Cat. No. 554603) to stimulate CTLL-2 cells at 2x10^4 cells/mL as indicator cells (i.e. preincubation of the antibody with recombinant human IL-2 for 60 minutes).
    50% Neutralization (ND50) at 0.1-1.5 µg/mL
    >95% Neutralization at 3 - 15 myg/mL
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    免疫原
    Human IL-2 Recombinant Protein
    克隆位点
    MQ1-17H12
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IL2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

    Andersson, Abrams, Björk, Funa, Litton, Agren, Andersson: "Concomitant in vivo production of 19 different cytokines in human tonsils." in: Immunology, Vol. 83, Issue 1, pp. 16-24, (1995) (PubMed).

    Fernandez, Andersson, Andersson, Troye-Blomberg: "Cytokine synthesis analyzed at the single-cell level before and after revaccination with tetanus toxoid." in: European journal of immunology, Vol. 24, Issue 8, pp. 1808-15, (1994) (PubMed).

    Gillis, Ferm, Ou, Smith: "T cell growth factor: parameters of production and a quantitative microassay for activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 120, Issue 6, pp. 2027-32, (1978) (PubMed).

  • 抗原
    IL-2 (IL2) (Interleukin 2 (IL2))
    别名
    IL-2 (IL2 产品)
    别名
    IL2 antibody, IL-2 antibody, il2 antibody, TCGF antibody, lymphokine antibody, Il-2 antibody, POIL2 antibody, interleukin 2 antibody, interleukin-15 antibody, IL2 antibody, il2 antibody, LOC100303688 antibody, Il2 antibody
    背景
    The MQ1-17H12 antibody reacts with human interleukin-2 (IL-2). The immunogen used to generate the MQ1-17H12 hybridoma was recombinant human IL-2. Unconjugated or purified forms of this antibody have been reported to be neutralizing for human IL-2 bioactivity.
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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