CD3 MOLCPX 抗体
This anti- antibody is a 大鼠 单克隆 antibody detecting in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 2+ publications.
(2 references)Quick Overview for CD3 MOLCPX 抗体 (ABIN1176868)
抗原
CD3 MOLCPX
适用
小鼠
宿主
大鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS)
克隆位点
17A2
-
-
品牌
- BD Pharmingen™
-
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
-
免疫原
- gammadelta TCR-positive T-T hybridoma D1
-
亚型
- IgG2b kappa
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.0 mg/mL
-
缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
-
储存液
- Azide free
-
储存条件
- 4 °C
-
储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
-
-
: "Antilymphocytic antibodies and marrow transplantation. XII. Suppression of graft-versus-host disease by T-cell-modulating and depleting antimouse CD3 antibody is most effective when preinjected in ..." in: Blood, Vol. 80, Issue 10, pp. 2661-7, (1992) (PubMed).
: "Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex." in: Immunology letters, Vol. 23, Issue 2, pp. 113-8, (1990) (PubMed).
-
: "Antilymphocytic antibodies and marrow transplantation. XII. Suppression of graft-versus-host disease by T-cell-modulating and depleting antimouse CD3 antibody is most effective when preinjected in ..." in: Blood, Vol. 80, Issue 10, pp. 2661-7, (1992) (PubMed).
-
- CD3 MOLCPX
-
背景
-
The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes. Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells. The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11. This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain. In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells.
Synonyms: CD3, CD3 epsilon, Cd3e, CD3epsilon, T3e
抗原
-
You are here:
