IL1RL1 抗体
Quick Overview for IL1RL1 抗体 (ABIN1169349)
抗原
See all IL1RL1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes soluble human ST2. Detects a band of ~50 kDa by Western blot and the endogenous ST2 by Flow Cytometry.
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交叉反应
- 人
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human soluble ST2.
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anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 162-349) antibody
IL1RL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) antibodyIL1RL1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal ST33868 unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) antibodyIL1RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 207-220) antibodyIL1RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 38-87) antibodyIL1RL1 适用: 人, 小鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) antibodyIL1RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 357-532) antibodyIL1RL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (N-Term) antibodyIL1RL1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- In PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
有效期
- 6 months
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- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
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别名
- ST2
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背景
- ST2 is a member of the Toll/IL-1 receptor family. Two forms of the protein exist, a soluble form known as ST2 and a membrane anchored form known as ST2L. The membrane form is expressed by Th2 cells and bone marrow derived mast cells, whereas the soluble form is expressed by serum-stimulated fibroblasts. It binds IL-33 and is structurally similar to IL-1R1. Type 2 innate lymphoid cells (ILC2), originally referred to as natural helper (NH) cells, are a novel target of IL-33. Lung ILC2s participate in the induction of airway inflammation in influenza virus-infected mice and papain-administrated mice. Soluble ST2 plays a role in protecting ILC2 from IL-33 stimulation and thereby maintaining them in a naive state and might be important for the regulation of several disease. Blocking with anti-ST2 antibodies has been shown to alleviate experimental arthritis and airway inflammation. The IL-33-ST2 axis is is involved across a range of diseases including asthma, allergies, obesity and cardiac disease.
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UniProt
- Q01638
抗原
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