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TNFSF18 抗体

The 兔 多克隆 anti-TNFSF18 antibody (ABIN1169328) specifically detects TNFSF18 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN1169328
发货至: 中国
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Room 801-803
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Quick Overview for TNFSF18 抗体 (ABIN1169328)

抗原

See all TNFSF18 抗体
TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))

适用

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宿主

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克隆类型

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多克隆

标记

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This TNFSF18 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 原理

    anti-GITRL (human), pAb

    特异性

    Recognizes human GITRL. Detects a band of ~15-17 kDa by Western blot. Does not cross-react with mouse GITRL.

    无交叉反应

    小鼠

    交叉反应 (详细)

    Does not cross-react with mouse GITRL.

    产品特性

    Polyclonal Antibody. Recognizes human GITRL. Detects a band of ~15-17 kDa by Western blot. Does not cross-react with mouse GITRL. Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, .). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human GITRL.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4.

    储存液

    Without preservative

    注意事项

    After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    +4°C

    -20°C

    Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • 抗原

    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))

    别名

    GITRL

    背景

    Alternate Names/Synonyms: Glucocorticoid-induced TNF Receptor Ligand, AITRL, Activation-inducible TNF-related Ligand, TNFSF18

    Product Description: GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, ..). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.

    UniProt

    Q9UNG2
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