TNFSF18 抗体
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北京 101111
Quick Overview for TNFSF18 抗体 (ABIN1169328)
抗原
See all TNFSF18 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human GITRL. Detects a band of ~15-17 kDa by Western blot.
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交叉反应
- 人
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无交叉反应
- 小鼠
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交叉反应 (详细)
- Does not cross-react with mouse GITRL.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human GITRL.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
有效期
- 6 months
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- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
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别名
- GITRL
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背景
- GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, ..). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
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UniProt
- Q9UNG2
抗原
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