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IDO1 抗体

This anti-IDO1 antibody is a 兔 多克隆 antibody detecting IDO1 in WB, ELISA, IHC 和 ICC. Suitable for 小鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1169195
发货至: 中国

Quick Overview for IDO1 抗体 (ABIN1169195)

抗原

See all IDO1 抗体
IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

适用

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小鼠

宿主

  • 77
  • 16
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克隆类型

  • 68
  • 27
  • 1
多克隆

标记

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  • 1
  • 1
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  • 1
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This IDO1 antibody is un-conjugated

应用范围

  • 74
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  • 16
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • 特异性

    Recognizes mouse IDO. Detects a band of ~45 kDa by Western blot.

    交叉反应

    小鼠

    过滤

    0.2 μm filtered

    免疫原

    Recombinant mouse IDO.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • Jung, Lee, Chang, Lee, Jeong, Lee, Park, Han, Seo, Lee, Park: "Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 5, pp. 3146-54, (2009) (PubMed).

    Yen, Lin, Chen, Huang, Yang, Chang, Lei, Lai: "A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 2, pp. 641-9, (2009) (PubMed).

    Cook, Bickerstaff, Wang, Nadasdy, Della Pelle, Colvin, Orosz: "Spontaneous renal allograft acceptance associated with "regulatory" dendritic cells and IDO." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 5, pp. 3103-12, (2008) (PubMed).

    Yadav, Burudi, Alirezaei, Flynn, Watry, Lanigan, Fox: "IFN-gamma-induced IDO and WRS expression in microglia is differentially regulated by IL-4." in: Glia, Vol. 55, Issue 13, pp. 1385-96, (2007) (PubMed).

  • 抗原

    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

    别名

    IDO

    背景

    IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

    UniProt

    P28776

    途径

    Activated T Cell Proliferation
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