IL-37 抗体
Our Local Distributor
北京 101111
Quick Overview for IL-37 抗体 (ABIN1169178)
抗原
See all IL-37 (IL37) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Recognizes human IL-37. Detects a band of ~30 kDa by Western blot.
-
交叉反应
- 人
-
过滤
- 0.2 μm filtered
-
免疫原
- Recombinant human IL-37.
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
有效期
- 6 months
-
-
- IL-37 (IL37) (Interleukin 37 (IL37))
-
别名
- IL-37
-
背景
- IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
-
UniProt
- Q9NZH6
抗原
-