IL-33 抗体
(4 references)Quick Overview for IL-33 抗体 (ABIN1169172)
抗原
See all IL-33 (IL33) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes human IL-33.
-
交叉反应
- 人
-
无交叉反应
- 小鼠
-
交叉反应 （详细）
- Does not cross-react with mouse IL-33.
-
过滤
- 0.2 μm filtered
-
免疫原
- Recombinant human IL-33.
-
亚型
- IgG2a
-
-
anti-Interleukin 33 (IL33) (AA 112-270) antibody
IL33 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C11 unconjugated
anti-Interleukin 33 (IL33) (AA 110-261) antibodyIL33 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Interleukin 33 (IL33) (AA 185-264) antibodyIL33 适用: 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) (AA 171-269) antibodyIL33 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Interleukin 33 (IL33) (AA 102-264) antibodyIL33 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, IHC (p), EIA, Func 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibody (Biotin)IL33 适用: 人 WB, EIA 宿主: 兔 Polyclonal Biotin
anti-Interleukin 33 (IL33) (AA 1-111) antibodyIL33 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) (AA 123-276) antibodyIL33 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
-
-
-
: "Cigarette smoke alters IL-33 expression and release in airway epithelial cells." in: Biochimica et biophysica acta, Vol. 1842, Issue 9, pp. 1630-7, (2014) (PubMed).
: "Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis." in: Arthritis and rheumatism, Vol. 60, Issue 3, pp. 738-49, (2009) (PubMed).
: "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. ..." in: Molecular psychiatry, Vol. 14, Issue 11, pp. 1004-16, (2009) (PubMed).
: "Interleukin-33 is biologically active independently of caspase-1 cleavage." in: The Journal of biological chemistry, Vol. 284, Issue 29, pp. 19420-6, (2009) (PubMed).
-
: "Cigarette smoke alters IL-33 expression and release in airway epithelial cells." in: Biochimica et biophysica acta, Vol. 1842, Issue 9, pp. 1630-7, (2014) (PubMed).
-
- IL-33 (IL33) (Interleukin 33 (IL33))
-
别名
- IL-33
-
背景
- Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL33 is converted by CASP1 to a 18 kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
-
UniProt
- O95760
-
途径
- Production of Molecular Mediator of Immune Response
抗原
-
