电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

IL-33 抗体

IL33 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1169164
发货至: 中国
  • 抗原 See all IL-33 (IL33) 抗体
    IL-33 (IL33) (Interleukin 33 (IL33))
    适用
    • 81
    • 45
    • 37
    • 9
    • 1
    小鼠
    宿主
    • 102
    • 26
    • 4
    • 3
    • 2
    • 1
    • 1
    克隆类型
    • 110
    • 29
    多克隆
    标记
    • 69
    • 21
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-33 antibody is un-conjugated
    应用范围
    • 83
    • 67
    • 35
    • 25
    • 18
    • 15
    • 14
    • 14
    • 11
    • 10
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    特异性
    Recognizes mouse IL-33. Detects a band of ~18 kDa by Western blot.
    交叉反应
    小鼠
    无交叉反应
    交叉反应 (详细)
    Does not cross-react with human IL-33.
    过滤
    0.2 μm filtered
    免疫原
    Recombinant mouse IL-33.
    Top Product
    Discover our top product IL33 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • Hayakawa, Hayakawa, Kume, Tominaga: "Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26369-80, (2007) (PubMed).

  • 抗原
    IL-33 (IL33) (Interleukin 33 (IL33))
    别名
    IL-33 (IL33 产品)
    别名
    IL33 antibody, C9orf26 antibody, DVS27 antibody, IL1F11 antibody, NF-HEV antibody, NFEHEV antibody, RP11-575C20.2 antibody, 9230117N10Rik antibody, Il-33 antibody, Il1f11 antibody, RGD1311155 antibody, interleukin 33 antibody, IL33 antibody, Il33 antibody
    背景
    Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL33 is converted by CASP1 to a 18 kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
    UniProt
    Q8BVZ5
    途径
    Production of Molecular Mediator of Immune Response
You are here:
客服