IL-33 抗体
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北京 101111
Quick Overview for IL-33 抗体 (ABIN1169164)
抗原
See all IL-33 (IL33) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes mouse IL-33. Detects a band of ~18 kDa by Western blot.
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交叉反应
- 小鼠
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无交叉反应
- 人
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交叉反应 （详细）
- Does not cross-react with human IL-33.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant mouse IL-33.
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anti-Interleukin 33 (IL33) (AA 112-270) antibody
IL33 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C11 unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, ELISA, IHC, IP, Func 宿主: 小鼠 Monoclonal IL33305B unconjugated
anti-Interleukin 33 (IL33) (AA 112-270) antibodyIL33 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C19 unconjugated
anti-Interleukin 33 (IL33) (AA 110-261) antibodyIL33 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Interleukin 33 (IL33) (AA 185-264) antibodyIL33 适用: 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) (AA 171-269) antibodyIL33 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Interleukin 33 (IL33) (AA 102-264) antibodyIL33 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, IHC (p), EIA, Func 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibody (Biotin)IL33 适用: 人 WB, EIA 宿主: 兔 Polyclonal Biotin
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
有效期
- 6 months
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: "Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26369-80, (2007) (PubMed).
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: "Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26369-80, (2007) (PubMed).
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- IL-33 (IL33) (Interleukin 33 (IL33))
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别名
- IL-33
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背景
- Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL33 is converted by CASP1 to a 18 kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
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UniProt
- Q8BVZ5
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途径
- Production of Molecular Mediator of Immune Response
抗原
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