SIRT6 抗体
Quick Overview for SIRT6 抗体 (ABIN1169069)
抗原
See all SIRT6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human sirtuin 6. Detects a band of ~47 kDa by Western blot.
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交叉反应
- 人
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human sirtuin 6.
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亚型
- IgG2b
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anti-Sirtuin 6 (SIRT6) (AA 1-334) antibody
SIRT6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2G1H1 unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 适用: 人, 小鼠, 大鼠, 猴 WB, IP, IF 宿主: 小鼠 Monoclonal 6C9-D10-D3 unconjugated
anti-Sirtuin 6 (SIRT6) (Middle Region) antibodySIRT6 适用: 人, 大鼠, 犬, Cow WB, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (N-Term) antibodySIRT6 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 35-274) antibodySIRT6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 适用: 人, 大鼠, 犬, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 56-105) antibodySIRT6 适用: 人, 小鼠, 犬, 猴, Pig, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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- SIRT6 (Sirtuin 6 (SIRT6))
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别名
- Sirtuin 6
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背景
- Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.
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UniProt
- Q8N6T7
抗原
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