SIRT6 抗体
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北京 101111
Quick Overview for SIRT6 抗体 (ABIN1169068)
抗原
See all SIRT6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- anti-Sirtuin 6 (human), pAb
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特异性
- Recognizes human sirtuin 6. Detects a band of ~42 kDa by Western blot.
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产品特性
- Polyclonal Antibody. Recognizes human sirtuin 6. Detects a band of ~42 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human sirtuin 6.
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anti-Sirtuin 6 (SIRT6) (AA 141-250) antibody
SIRT6 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2G1H1 unconjugated
anti-Sirtuin 6 (SIRT6) (AA 1-334) antibodySIRT6 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 14-180) antibodySIRT6 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 适用: 人, 小鼠, 大鼠, 猴 WB, IP, IF 宿主: 小鼠 Monoclonal 6C9-D10-D3 unconjugated
anti-Sirtuin 6 (SIRT6) (AA 290-319), (C-Term) antibodySIRT6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2109 unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1135 unconjugated Recombinant Antibody
anti-Sirtuin 6 (SIRT6) (Middle Region) antibodySIRT6 适用: 人, 大鼠, 犬, Cow WB, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (N-Term) antibodySIRT6 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 56-105) antibodySIRT6 适用: 人, 小鼠, 犬, 猴, Pig, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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有效期
- 6 months
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- SIRT6 (Sirtuin 6 (SIRT6))
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别名
- Sirtuin 6
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背景
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Alternate Names/Synonyms: SIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6
Product Description: Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.
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UniProt
- Q8N6T7
抗原
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