SIRT6 抗体
-
- 抗原 See all SIRT6 抗体
- SIRT6 (Sirtuin 6 (SIRT6))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SIRT6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- Recognizes human sirtuin 6. Detects a band of ~42 kDa by Western blot.
- 交叉反应
- 人
- 过滤
- 0.2 μm filtered
- 免疫原
- Recombinant human sirtuin 6.
- Top Product
- Discover our top product SIRT6 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
-
- 抗原
- SIRT6 (Sirtuin 6 (SIRT6))
- 别名
- Sirtuin 6 (SIRT6 产品)
- 背景
- Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.
- UniProt
- Q8N6T7
-