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TRIB3 抗体 (AA 112-125)
TRIB3
适用: 人
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
TRIB3抗体详情
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抗原
See all TRIB3 抗体
TRIB3
(Tribbles Homolog 3 (Drosophila) (TRIB3))
抗原表位
All epitopes for TRIB3 抗体
AA 112-125
适用
All reactivities for TRIB3 抗体
人
宿主
All hosts for TRIB3 抗体
兔
克隆类型
All clonalities for TRIB3 抗体
多克隆
标记
All conjugates for TRIB3 抗体
This TRIB3 antibody is un-conjugated
应用范围
All applications for TRIB3 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
特异性
Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa).
交叉反应
人
过滤
0.2 μm filtered
免疫原
Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
Lot specific
缓冲液
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
储存液
Without preservative
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C.
有效期
6 months
TRIB3目标详情
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抗原
TRIB3
(Tribbles Homolog 3 (Drosophila) (TRIB3))
别名
TRB-3 (TRIB3 产品 )
别名
zgc:76966 antibody, TRIB3 antibody, C20orf97 antibody, NIPK antibody, SINK antibody, SKIP3 antibody, TRB3 antibody, Ifld2 antibody, Nipk antibody, TRB-3 antibody, Trb3 antibody, tribbles pseudokinase 3 antibody, trib3 antibody, TRIB3 antibody, Trib3 antibody
背景
Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
UniProt
Q96RU7
途径
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Lipid Metabolism by PPARalpha
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