TRIB3 抗体 (AA 112-125)
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北京 101111
Quick Overview for TRIB3 抗体 (AA 112-125) (ABIN1169021)
抗原
See all TRIB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 112-125
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原理
- anti-TRB-3 (human), pAb
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特异性
- Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa).
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产品特性
- Polyclonal Antibody. Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa). Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
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过滤
- 0.2 μm filtered
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免疫原
- Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.
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anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibody
TRIB3 适用: 人 WB, IF, RNAi 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibodyTRIB3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 15-45), (N-Term) antibodyTRIB3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4069-RB4070 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) antibodyKD Validated TRIB3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4690 unconjugated Recombinant Antibody
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (N-Term) antibodyTRIB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 152-325) antibodyTRIB3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (C-Term) antibodyTRIB3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 201-300) antibodyTRIB3 适用: 人 FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 301-331), (C-Term) antibodyTRIB3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB4072 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (Internal Region) antibodyTRIB3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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有效期
- 6 months
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- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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别名
- TRB-3
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背景
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Alternate Names/Synonyms: Tribbles Homolog 3, Neuronal Cell death-inducible Putative Kinase, SINK, p65-interacting Inhibitor of NF-kappaB
Product Description: Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
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UniProt
- Q96RU7
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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