BMP2 抗体
Quick Overview for BMP2 抗体 (ABIN116465)
抗原
See all BMP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes Human BMP2. Other species not tested.
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纯化方法
- Affinity Chromatography employing immobilized Human BMP-2 matrix
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免疫原
- Highly pure (>98%) E.coli derived recombinant Human BMP-2.
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anti-Bone Morphogenetic Protein 2 (BMP2) (AA 281-394) antibody
BMP2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) antibodyBMP2 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 9E10G12 unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 283-365) antibodyBMP2 适用: 人, 小鼠, 大鼠, 兔, 绵羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) antibodyBMP2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 24-395) antibodyBMP2 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 283-396) antibodyBMP2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 9E10D6 unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 49-243) antibodyBMP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (C-Term) antibodyBMP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 24-396) antibodyBMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 2 (BMP2) (AA 284-388) antibody (APC)BMP2 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC
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应用备注
- NeutralizationTo yield one-half maximal inhibition [ND50] of the biological activity of hBMP-2 (200 ng/mL), a concentration of 1.3-1.9 μg/mL of this antibody is required. ELISAIndirect: To detect hBMP-2 by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL of this antibody is required. This antibody, in conjunctionwith compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hBMP-2. Sandwich: To detect hBMP-2 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with a biotinylated Anti-Human BMP-2 (PP1219B) as a detectionantibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hBMP-2. Western BlotTo detect hBMP-2 by Western Blot analysis this antibody can be used at a concentration of0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hBMP-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducingconditions.
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限制
- 仅限研究用
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溶解方式
- Centrifuge the vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
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别名
- BMP2 / BMP2A
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背景
- BMP2 belongs to the transforming growth factor beta (TGFB) superfamily of secreted growth factors. It is a disulfide linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.Synonyms: BMP-2, BMP-2A, Bone morphogenetic protein 2
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基因ID
- 650
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NCBI登录号
- NP_001191
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UniProt
- P12643
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
抗原
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