IL18BP 抗体
Quick Overview for IL18BP 抗体 (ABIN116421)
抗原
See all IL18BP 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity chromatography.
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免疫原
- Highly pure (>98%) recombinant mIL-18P.
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anti-Interleukin 18 Binding Protein (IL18BP) (AA 29-193) antibody
IL18BP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (AA 31-194) antibodyIL18BP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (AA 91-194) antibodyIL18BP 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (AA 31-194) antibodyIL18BP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (C-Term) antibodyIL18BP 适用: 人, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) antibodyIL18BP 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (AA 29-193) antibodyIL18BP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (AA 31-194) antibodyIL18BP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 5-2# unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (AA 29-193) antibodyIL18BP 适用: 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 18 Binding Protein (IL18BP) (AA 31-183) antibodyIL18BP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neutralization. ELISA: To detect mIL-18BP by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant mIL-18BP. Western Blot: To detect mIL-18BP by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant mIL-18BP is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of > 0.2 mg/mL.
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缓冲液
- 0.5 X PBS, pH 7.4 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- IL18BP (Interleukin 18 Binding Protein (IL18BP))
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别名
- IL18BP
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背景
- IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. IL18 also has other biological properties such as stimulation of Fas ligand expression, and induction of CC and CXC chemokines. IL18 increases production of competent HIV. IL18 is related to the IL1 family. One of the IL18 receptor chains is the IL1 receptor-related protein, a member of the IL 1R family. Like IL1 , IL18 is first synthesized as a leaderless precursor requiring the IL1 converting enzyme (ICE) for cleavage into an active molecule. IL18 may play a role in tissue injury in inflammatory reactions.Synonyms: IL-18BP, Interleukin-18-binding protein, Tadekinig-alfa
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基因ID
- 16068
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NCBI登录号
- NP_034661
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UniProt
- Q9Z0M9
抗原
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