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IL18BP 抗体 (Biotin)

This anti-IL18BP antibody is a 山羊 多克隆 antibody detecting IL18BP in WB 和 EIA. Suitable for 小鼠.
产品编号 ABIN116419
发货至: 中国

Quick Overview for IL18BP 抗体 (Biotin) (ABIN116419)

抗原

See all IL18BP 抗体
IL18BP (Interleukin 18 Binding Protein (IL18BP))

适用

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小鼠

宿主

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山羊

克隆类型

  • 67
  • 9
  • 2
多克隆

标记

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This IL18BP antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody recognizes Mouse IL18BP

    纯化方法

    Affinity Chromatography.

    免疫原

    Highly pure (>98%) E.coli derived recombinant Murine IL-18BP.
  • 应用备注

    ELISA: To detect mIL-18BP by direct ELISA (using 100 l/well antibody solution) thisantibody can be used at a concentration of 0.15-0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinantmIL-18BP. Western Blot: To detect mIL-18BP by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant mIL-18BP is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile PBS solution containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    IL18BP (Interleukin 18 Binding Protein (IL18BP))

    别名

    IL18BP

    背景

    IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. IL18 also has other biological properties such as stimulation of Fas ligand expression, and induction of CC and CXC chemokines. IL18 increases production of competent HIV. IL18 is related to the IL1 family. One of the IL18 receptor chains is the IL1 receptor-related protein, a member of the IL 1R family. Like IL1 , IL18 is first synthesized as a leaderless precursor requiring the IL1 converting enzyme (ICE) for cleavage into an active molecule. IL18 may play a role in tissue injury in inflammatory reactions.Synonyms: IL-18BP, Interleukin-18-binding protein, Tadekinig-alfa

    基因ID

    16068

    NCBI登录号

    NP_034661

    UniProt

    Q9Z0M9
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