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CXCL10 抗体

This anti-CXCL10 antibody is a 兔 多克隆 antibody detecting CXCL10 in WB, EIA 和 Func. Suitable for 小鼠.
产品编号 ABIN116271
发货至: 中国

Quick Overview for CXCL10 抗体 (ABIN116271)

抗原

See all CXCL10 抗体
CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This CXCL10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
  • 特异性

    Reacts with Interferon-gamma Inducible Protein-10

    纯化方法

    Affinity Chromatography using an immobilizedd Murine IP-10 Matrix

    免疫原

    Highly pure (>98%) E.coli derived recombinant Mouse IP-10.
  • 应用备注

    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofMouse IP-10 (100 ng/mL), a concentration of 10.0 μg/mL of this antibody is required. Sandwich ELISA: To detect Mouse IP-10 by Sandwich ELISA (using 100 ml/well antibodysolution), a concentration of 0.5-2.0 μg/mL of this antibody is required. This Biotinylatedantibody, in conjuction with anti Mouse IP10 antibody (cat. PP1083B) as a Detectionantibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Mouse IP-10. Western Blot: To detect Mouse IP-10 by Western Blot analysis this antibody can be used ata concentration of 0.1 -0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant Mouse IP-10 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2 without preservatives

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

    别名

    CXCL10 / IP-10

    背景

    Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.Synonyms: 10 kDa interferon-gamma-induced protein, C-X-C motif chemokine 10, Gamma-IP10, INP10, SCYB10, Small-inducible cytokine B10

    基因ID

    15945

    NCBI登录号

    NP_067249

    UniProt

    P17515
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