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CCL5 抗体

This anti-CCL5 antibody is a 兔 多克隆 antibody detecting CCL5 in WB, Func, EIA 和 IHC (p). Suitable for 人.
产品编号 ABIN116219
发货至: 中国

Quick Overview for CCL5 抗体 (ABIN116219)

抗原

See all CCL5 抗体
CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

适用

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宿主

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克隆类型

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多克隆

标记

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This CCL5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    Recognizes Human RANTES.

    纯化方法

    Affinity Chromatography employing immobilized hRANTES matrix.

    免疫原

    Highly pure (>98%) derived recombinant Human RANTES.
  • 应用备注

    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhRANTES (100 ng/mL), a concentration of 5.0 - 7.0 μg/mL of this antibody is required. ELISA: To detect hRANTES by direct ELISA (using 100l/well antibody solution) aconcentration of at least 0.5g/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 -0.4 ng/well of recombinant hRANTES. Western Blot: To detect hRANTES by Western Blot analysis this antibody can be used at aconcentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hRANTES is 1.5 - 3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2 without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

    别名

    RANTES / CCL5

    背景

    Rantes, also known as CCL5, is the protein classified as a chemotactic cytokine or chemokine. This protein is a chemotactic for blood monocytes, memory T helper cells, eosinophils and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. Rantes also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. It is also an HIV-suppressive factor released from CD8+ T cells.Synonyms: C-C motif chemokine 5, D17S136E, E °CP, Eosinophil-chemotactic cytokine, SCYA5, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES, cell-specific protein P228

    基因ID

    6352

    NCBI登录号

    NP_002976

    UniProt

    P13501

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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