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CXCL10 抗体

This anti-CXCL10 antibody is a 兔 多克隆 antibody detecting CXCL10 in WB, EIA 和 Func. Suitable for 人.
产品编号 ABIN116123
发货至: 中国

Quick Overview for CXCL10 抗体 (ABIN116123)

抗原

See all CXCL10 抗体
CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

适用

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宿主

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克隆类型

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多克隆

标记

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This CXCL10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
  • 纯化方法

    Affinity Chromatography employing immobilized Human IP-10 matrix.

    免疫原

    Highly pure (>98%) recombinant Human IP-10
  • 应用备注

    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhIP-10 (100.0 ng/mL), a concentration of 2-3 μg/mL of this antibody is required. ELISA: To detect hIP-10 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hIP-10. Western Blot: To detect hIP-10 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIP-10 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2 without preservatives

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized antibody is stable at -20 °C. The reconstituted antibody is stable for at least two weeks at 2-8 °C Frozen aliquots are stable for at least 6 months when stored at -20 °C.

    有效期

    6 months
  • 抗原

    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

    别名

    CXCL10 / IP-10

    背景

    Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.Synonyms: 10 kDa interferon-gamma-induced protein, C-X-C motif chemokine 10, Gamma-IP10, INP10, SCYB10, Small-inducible cytokine B10

    基因ID

    9606

    UniProt

    P02778
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