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IL-11 抗体

IL11 适用: 人 WB, EIA, Func 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN116103
发货至: 中国
  • 抗原 See all IL-11 (IL11) 抗体
    IL-11 (IL11) (Interleukin 11 (IL11))
    适用
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    宿主
    • 46
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    克隆类型
    • 47
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    多克隆
    标记
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    This IL-11 antibody is un-conjugated
    应用范围
    • 45
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody detects IL11.
    纯化方法
    Affinity Chromatograophy employing immobilized hIL-11 matrix
    免疫原
    Highly pure (>98%) recombinant hIL-11. Remarks: Molecular Weight: ~150 kDa
    Top Product
    Discover our top product IL11 Primary Antibody
  • 应用备注
    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhIL-11 (1.50 ng/mL), a concentration of 0.02-0.05 μg/mL of this antibody is required. Sandwich ELISA: To detect Human IL-11 by Sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with Biotinylated anti IL11 antibody (PP1033B1 orPP1033B2) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well ofrecombinant Human IL-11. Western Blot: To detect Human IL-11 by Western Blot analysis this antibody can be used ata concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-11 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized antibody is stable for one year from date of receipt at -20 °C. The reconstituted antibody is stable for one month at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
    有效期
    12 months
  • 抗原
    IL-11 (IL11) (Interleukin 11 (IL11))
    别名
    Interleukin-11 / IL11 (IL11 产品)
    别名
    IL11 antibody, AGIF antibody, IL-11 antibody, Il-11 antibody, interleukin 11 antibody, IL11 antibody, Il11 antibody
    背景
    Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.Synonyms: AGIF, Adipogenesis inhibitory factor, IL-11
    基因ID
    3589
    NCBI登录号
    NP_000632
    UniProt
    P20809
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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