IL-11 抗体
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北京 101111
Quick Overview for IL-11 抗体 (ABIN116103)
抗原
See all IL-11 (IL11) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects IL11.
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纯化方法
- Affinity Chromatograophy employing immobilized hIL-11 matrix
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免疫原
- Highly pure (>98%) recombinant hIL-11. Remarks: Molecular Weight: ~150 kDa
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anti-Interleukin 11 (IL11) (AA 22-199) antibody
IL11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 22-120) antibodyIL11 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 27-61) antibodyIL11 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56890 unconjugated
anti-Interleukin 11 (IL11) (AA 25-74) antibodyIL11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Interleukin 11 (IL11) antibody (Biotin)IL11 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 11 (IL11) (AA 25-199) antibodyIL11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (N-Term) antibodyIL11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhIL-11 (1.50 ng/mL), a concentration of 0.02-0.05 μg/mL of this antibody is required. Sandwich ELISA: To detect Human IL-11 by Sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with Biotinylated anti IL11 antibody (PP1033B1 orPP1033B2) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well ofrecombinant Human IL-11. Western Blot: To detect Human IL-11 by Western Blot analysis this antibody can be used ata concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-11 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- The lyophilized antibody is stable for one year from date of receipt at -20 °C. The reconstituted antibody is stable for one month at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
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有效期
- 12 months
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- IL-11 (IL11) (Interleukin 11 (IL11))
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别名
- Interleukin-11 / IL11
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背景
- Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.Synonyms: AGIF, Adipogenesis inhibitory factor, IL-11
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基因ID
- 3589
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NCBI登录号
- NP_000632
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UniProt
- P20809
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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