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CXCL2 抗体

This anti-CXCL2 antibody is a 兔 多克隆 antibody detecting CXCL2 in WB, EIA 和 Func. Suitable for 人.
产品编号 ABIN116031
发货至: 中国

Quick Overview for CXCL2 抗体 (ABIN116031)

抗原

See all CXCL2 抗体
CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CXCL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
  • 特异性

    This antibody detects GRO-beta.

    纯化方法

    Affinity Chromatography employing immobilized hGRO-beta matrix.

    免疫原

    Highly pure (>98%) recombinant hGRO-beta (human GRO-beta)
  • 应用备注

    Neutralization(To yield one-half maximal inhibition [ND50] of the biological activity of hGRO-beta (100.00 ng/mL), a concentration of 0.5-1.0 μg/mL of this antibody has been used with previous lots)ELISA(Indirect): To detect hGRO-beta by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant hGRO-beta. (Sandwich): To detect hGRO-beta by sandwich ELISA (using 100 μL/well antibody solution)a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with biotinylated anti-Human GRO-beta as a detection antibody,allows the detection of at least 0.2 - 0.4 ng/well of recombinant hGRO-beta. Western BlotTo detect hGRO-beta by Western Blot analysis this antibody can be used at a concentrationof 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hGRO-beta is 1.5-3.0 ng/lane, under either reducing or non-reducing

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized antibody is stable at -20 °C for one year from despatch. The reconstituted antibody is stable for two weeks at 2-8 °C. Frozen aliquots are stable for six months when stored at -20 °C.

    有效期

    12 months
  • 抗原

    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

    别名

    CXCL2 / MIP2A

    背景

    GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60 % amino acid homology to human GRO alpha and GRO gamma.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2

    基因ID

    2920

    NCBI登录号

    NP_002080

    UniProt

    P19875

    途径

    Cellular Response to Molecule of Bacterial Origin
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