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CX3CL1 抗体

This anti-CX3CL1 antibody is a 兔 多克隆 antibody detecting CX3CL1 in WB, IHC (p), EIA 和 Func. Suitable for 人.
产品编号 ABIN116017
发货至: 中国

Quick Overview for CX3CL1 抗体 (ABIN116017)

抗原

See all CX3CL1 抗体
CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CX3CL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Functional Studies (Func)
  • 特异性

    This antibody is specific to Human Fractalkine.

    纯化方法

    Affinity Chromatography

    免疫原

    Highly pure (> 98%) E.coli derived recombinant Human Fractalkine (Cat.-No PA057). Remarks: Molecular Weight: ~150 kDa
  • 应用备注

    Neutralization. Sandwich ELISA: To detect Human Fractalkine by Sandwich ELISA (using 100 μL/wellantibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. Thisantigen affinity purified antibody, in conjunction with Biotinylated Anti-Human Fractalkine(PP1009B1 or PP1009B2) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human Fractalkine. Western Blot: To detect Human Fractalkine by Western Blot analysis this antibody can beused at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hFractalkine is 1.5-3.0 ng/lane, under eitherreducing or non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2 without preservatives

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • 抗原

    CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

    别名

    Fractalkine / CX3CL1

    背景

    CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. CX3CL1, a leukocyte chemoattractant, is expressed in various tissues including the brain, heart, lung, kidney, skeletal muscle, and testis. The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.Synonyms: C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, FKN, NTT, Neurotactin, SCYD1, Small-inducible cytokine D1

    基因ID

    6376

    NCBI登录号

    NP_002987

    UniProt

    P78423

    途径

    Synaptic Membrane
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