Cardiotrophin 1 抗体
Quick Overview for Cardiotrophin 1 抗体 (ABIN115989)
抗原
See all Cardiotrophin 1 (CTF1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts with Human Cardiotrophin-1
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纯化方法
- Affinity chromatography.
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免疫原
- Highly pure (>98%) recombinant hCardiotrophin-1.
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anti-Cardiotrophin 1 (CTF1) (AA 121-201) antibody
CTF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) antibodyCTF1 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB52510 unconjugated
anti-Cardiotrophin 1 (CTF1) (AA 1-201) antibodyCTF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) (AA 166-194), (C-Term) antibodyCTF1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) (AA 151-200) antibodyCTF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) (N-Term) antibodyCTF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) (AA 1-201) antibodyCTF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) (N-Term) antibodyCTF1 适用: 人, 大鼠, 小鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) (N-Term) antibodyCTF1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin 1 (CTF1) (AA 1-201) antibodyCTF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhCardiotrophin-1 (3 ng/mL), a concentration of 0.04-0.09 μg/mL of this antibody isrequired. ELISA: To detect hCardiotrophin-1 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hCardiotrophin-1. Western Blot: To detect hCardiotrophin-1 by Western Blot analysis this antibody can beused at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hCardiotrophin-1 is 1.5-3.0 ng/lane, underreducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- Cardiotrophin 1 (CTF1)
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别名
- Cardiotrophin-1
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背景
- Cardiotrophin-1 (CT-1), a cardiac hypertrophic factor, is a 21.5 kDa protein member of the IL-6 cytokine family. CT-1 is associated with the pathophysiology of heart diseases, including hypertension, myocardial infarction, valvular heart disease, and congestive heart failure. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF kappa B DNA -binding activities. CT-1 is highly expressed in the heart, skeletal muscle, prostate and ovary and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine.Synonyms: CT-1, CTF1
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基因ID
- 1489
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NCBI登录号
- NP_001136016
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UniProt
- Q16619
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途径
- JAK/STAT Signaling
抗原
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