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Cardiotrophin 1 抗体 (Biotin)

This anti-Cardiotrophin 1 antibody is a 兔 多克隆 antibody detecting Cardiotrophin 1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN115987
发货至: 中国

Quick Overview for Cardiotrophin 1 抗体 (Biotin) (ABIN115987)

抗原

See all Cardiotrophin 1 (CTF1) 抗体
Cardiotrophin 1 (CTF1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cardiotrophin 1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody reacts with Human Cardiotrophin-1.

    纯化方法

    Affinity chromatography.

    免疫原

    Highly pure (>98%) recombinant hCardiotrophin-1.
  • 应用备注

    ELISA: To detect hCardiotrophin-1 by direct ELISA (using 100 l/well antibody solution) thisantibody can be used at a concentration of 0.15-0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthCardiotrophin-1. Western Blot: To detect hCardiotrophin-1 by Western Blot analysis this antibody can beused at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hCardiotrophin-1 is 1.5-3.0 ng/lane, undereither reducing or non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2 without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    Cardiotrophin 1 (CTF1)

    别名

    Cardiotrophin-1

    背景

    Cardiotrophin-1 (CT-1), a cardiac hypertrophic factor, is a 21.5 kDa protein member of the IL-6 cytokine family. CT-1 is associated with the pathophysiology of heart diseases, including hypertension, myocardial infarction, valvular heart disease, and congestive heart failure. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF kappa B DNA -binding activities. CT-1 is highly expressed in the heart, skeletal muscle, prostate and ovary and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine.Synonyms: CT-1, CTF1

    基因ID

    1489

    NCBI登录号

    NP_001136016

    UniProt

    Q16619

    途径

    JAK/STAT Signaling
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