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CCL22 抗体

CCL22 适用: 人 WB, EIA, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN115780
发货至: 中国
  • 抗原 See all CCL22 抗体
    CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))
    适用
    • 47
    • 33
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    宿主
    • 63
    • 14
    • 1
    小鼠
    克隆类型
    • 63
    • 15
    单克隆
    标记
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    This CCL22 antibody is un-conjugated
    应用范围
    • 30
    • 26
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    • 13
    • 13
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    Recognises Human Macrophage Derived Chemokine (MDC)
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    highly pure (>98%) recombinant Human MDC
    亚型
    IgG1
    Top Product
    Discover our top product CCL22 Primary Antibody
  • 应用备注
    ELISA: In a sandwich ELISA (assuming 100 μL/well), a concentration of 2-4 μg/mL of thisantibody will detect at least 100 pg/mL of recombinant Human MDC when used withbiotinylated antigen affinity purified anti-Human MDC antibody (cat. PP1049B) as thedetection antibody at a concentration of at least 1 μg/mL. Western Blot: To detect Human MDC by Western Blot analysis this antibody can be used ata concentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hMDC is 0.25-0.50 ng/lane, undernon-reducing conditions. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhMIG (100 ng/mL), a concentration of 5.0-10.0 μg/mL of this antibody is required.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 1.0 mg/mL.
    缓冲液
    PBS without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))
    别名
    MDC / CCL22 (CCL22 产品)
    别名
    ABCD-1 antibody, DC/B-CK antibody, MDC antibody, SCYA22 antibody, STCP-1 antibody, DCBCK antibody, Scya22 antibody, Mdc antibody, CCL22 antibody, C-C motif chemokine ligand 22 antibody, chemokine (C-C motif) ligand 22 antibody, CCL22 antibody, Ccl22 antibody
    背景
    The MDC gene is one of several Cys-Cys (CC) cytokine genes which are clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by MDC displays chemotactic activity for natural killer cells, chronically activated T lymphocytes, monocytes and dendritic cells. It has no chemoattractant activity for eosinophils, neutrophils and resting T lymphocytes and also displays a mild activity for primary activated T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.Synonyms: C-C motif chemokine 22, CC chemokine STCP-1, Macrophage-derived chemokine, SCYA22, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1
    基因ID
    6367
    NCBI登录号
    NP_002981
    UniProt
    O00626
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