Resistin 抗体
Quick Overview for Resistin 抗体 (ABIN115514)
抗原
See all Resistin (RETN) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to Resistin.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Recombinant Human Resistin produced from E.Coli
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anti-Resistin (RETN) (AA 21-114) antibody
RETN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 21-114) antibodyRETN 适用: 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 17-108) antibodyRETN 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Resistin (RETN) (AA 45-114) antibodyRETN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 19-109) antibodyRETN 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 1-108) antibodyRETN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 0.1 mL of deionized water
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浓度
- 1.0 mg/mL
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缓冲液
- 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.
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有效期
- 6 months
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- Resistin (RETN)
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别名
- Resistin
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背景
- Resistin, a product of the RSTN gene, is a peptide hormone belonging to the class of cysteine-rich secreted proteins which is termed the RELM family, and is also described as ADSF (Adipose Tissue-Specific Secretory Factor) and FIZZ3 (Found in Inflammatory Zone). Human resistin contains 108 amino acids as a prepeptide, and its hydrofobic signal peptide is cleaved before its secretion. Resistin circulates in human blood as a dimeric protein consisting of two 92 amino acid polypeptides, which are disulfide-linked via Cys26. Resistin may be an important link between obesity and insulin resistance. Mouse resistin, specifically produced and secreted by adipocyte, acts on skeletal muscle myocytes, hepatocytes and adipocytes themselves so that it reduces their sensitivity to insulin. Steppan et al. have suggested that resistin suppresses the ability of insulin to stimulace glucose uptake. They have also suggested that resistin is present at elevated levels in blood of obese mice, and is down regulated by fasting and antidiabetic drugs. Way et al., on the other hand, have found that resistin expression is severly suppressed in obesity and is stimulated by several antidiabetic drugs. Other studies have shown that mouse resistin increases during the differentiation of adipocytes, but it also seems to inhibit adipogenesis. In contrast, the human adipogenic differentiation is likely to be associated with a down regulation of resistin gene expression. Recent studies have shown that human resistin is expressed also in macrophages and may be a novel link between inflammation and insulin resistance.Synonyms: ADSF, Adipose tissue-specific secretory factor, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3, HXCP1, RETN, RSTN
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基因ID
- 56729
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NCBI登录号
- NP_001180303
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UniProt
- Q9HD89
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途径
- Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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