This antibody reacts to ventricular myosin light chain.
纯化方法
Immunoaffinity chromatography
免疫原
Recombinant human myosin (cardiac) light chain fragment. Remarks: The antibody was raised in rabbits by immunization with the recombinant Human Myosin (Cardiac) Light Chain fragment. The amino acid sequence of the recombinant Human Myosin (Cardiac) Light Chain fragment is 100% homologous to the amino acid sequence of the human serum Myosin (Cardiac) Light Chain fragment.
ELISA. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
溶解方式
Restore with 0.05 mL of deionized water
浓度
1.0 mg/mL
缓冲液
0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
储存液
Azide free
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.
有效期
6 months
抗原
MYL3/CMLC1 (MYL3)
(Myosin, Light Chain 3 (MYL3))
别名
MYL3
背景
Human ventricular myosin light chain (MLC-I, Essential Myosin Light Chain Isoform) is a 21 kDa cardiac contractile protein, which is one of component of myosin structure. The protein MLC-I is present in the contractile apparatus and not in cytosol. In severe congestive heart failure (CHF), myofibrils may degenerate and, subsequently, the myofibrillar components may be released into the circulation. The increased blood levels of MLC-I could indicate morphological changes in CHF, myocardial infarction, structural abnormalities in viable myocytes also observed in non-ischaemic CHF, myocardial necrosis.Synonyms: CMLC1, Cardiac myosin light chain 1, MLC1SB, Myosin light chain 1, Myosin light chain 3, Ventricular/slow twitch myosin alkali light chain, slow-twitch muscle B/ventricular isoform