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Fetuin A 抗体

This 兔 多克隆 antibody specifically detects Fetuin A in WB, EIA 和 IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN115504
发货至: 中国
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Quick Overview for Fetuin A 抗体 (ABIN115504)

抗原

See all Fetuin A (AHSG) 抗体
Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

适用

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宿主

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克隆类型

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多克隆

标记

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This Fetuin A antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    This antibody reacts to Fetuin-A.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    Human serum
  • 应用备注

    ELISA. Western Blot. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 0.1 mL of deionized water

    浓度

    1.0 mg/mL

    缓冲液

    0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE

    储存液

    Azide free

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.

    有效期

    6 months
  • 抗原

    Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

    别名

    alpha-2-HS-Glycoprotein

    背景

    Fetuin-A (AHSG), a 59 kDa glycoprotein, consisting of two cystatin-like domains and a smaller unrelated domain, is predominantly sinthetized in liver . It is secreted into the blood stream and deposited as a noncollagenous protein in mineralized bones and teeth. Fetuin-A occurs in high serum concentrations during foetal life, whereas its level declines following infection, inflamatory and malignancy. Fetuin-A acts as an important circulating inhibitor of ectopic calcification, frequent complication of many degenerative diseases. Low serum level of Fetuin-A is associated with vascular and valvular calcification, atherosclerosis, malnutrition and higher cardiovascular mortality in chronic renal failure, liver cancer and liver cirrhosis patients on long-term dialysis. AHSG protein represents a natural inhibitor of tyrosinase kinase activity of the insulin receptor. It may play a significant role in regulating postprandial glucose disposal, insulin sensitivity, weight gain, and fat accumulation. The serum and bone-resident Fetuin-A binds to transforming growth factor- beta and blocks TGFbeta binding to cell surface receptors.Synonyms: AHSG, Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, FETUA, Fetuin A, PRO2743

    基因ID

    197

    NCBI登录号

    NP_001613

    UniProt

    P02765
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