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Chromogranin A 抗体 (C-Term)

The 兔 多克隆 anti-Chromogranin A antibody is suitable to detect Chromogranin A in samples from 人. It has been validated for IHC (p) 和 IHC (fro).
产品编号 ABIN115295
发货至: 中国
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Quick Overview for Chromogranin A 抗体 (C-Term) (ABIN115295)

抗原

See all Chromogranin A (CHGA) 抗体
Chromogranin A (CHGA)

适用

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宿主

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克隆类型

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多克隆

标记

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This Chromogranin A antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    C-Term

    特异性

    This antibody reacts with human Chromogranin A in the neuroendocrine cells and neural tissues. It does not recognizes the epitopes located on the N-terminal half of the chromogranin A molecule.
    Cellular Localization: Cytoplasmic.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Purified

    免疫原

    C-terminal half of chromogranin A was purified from urine of patients with carcinoid syndrome.
  • 应用备注

    Immunohistochemistry on Paraffin Embedded Sections: 1/20-1/50 in an ABC method(30-60 minutes at room temperature)Recommended Positive Control: Pancreas.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM Citrate buffer, pH 6.0 containing Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Chromogranin A (CHGA)

    别名

    Chromogranin A

    背景

    Chromogranin A (a protein of 439 amino acids which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.Synonyms: CHGA, CgA, Chromogranin-A, Pituitary secretory protein I, SP-I

    基因ID

    1113

    NCBI登录号

    NP_001266

    UniProt

    P10645

    途径

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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