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Ezrin 抗体 (AA 362-585)

Name: Ezrin 抗体 (AA 362-585)
SKU: ABIN115201
Availability: OutOfStock

This 小鼠单克隆 antibody specifically detects Ezrin in WB, IHC (p) 和 IP. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, Hamster 和 Kangaroo. It has been mentioned in 2+ publications

Formalin fixed paraffin embedded human lung stained with Ezrin antibody. (Ezrin 抗体 (AA 362-585))

IHC

1 image

(2 references)

产品编号 ABIN115201

发货至: 中国

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Quick Overview for Ezrin 抗体 (AA 362-585) (ABIN115201)

抗原

See all Ezrin (EZR) 抗体

Ezrin (EZR)

适用

人, 小鼠, 大鼠, Cow, Hamster, Kangaroo

宿主

小鼠

克隆类型

单克隆

标记

This Ezrin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

克隆位点

3C12

Discover our top product EZR Primary Antibody

抗原表位
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AA 362-585

特异性

This antibody reacts with a protein of 81 kDa.
Cellular Localization: Cell membrane

纯化方法

Purified

免疫原

BALB/C mice were immunized with a recombinant fragment of human ezrin corresponding to amino acid 362-585.

亚型

IgG1
anti-Ezrin (EZR) (AA 292-464) antibody
EZR 适用: 人, 小鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F1A9 unconjugated

anti-Ezrin (EZR) (AA 1-295) antibody
EZR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-586) antibody
EZR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (pTyr478) antibody
EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 1-586) antibody
EZR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1E11 unconjugated

anti-Ezrin (EZR) (pTyr353) antibody
EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) antibody
EZR 适用: 人 WB 宿主: 小鼠 Monoclonal CPTC-Ezrin-1 unconjugated

anti-Ezrin (EZR) (N-Term) antibody
EZR 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (AA 455-586) antibody
EZR 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Ezrin (EZR) (pThr567) antibody
EZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunoprecipitation. Western blot: 1: 100-750. Immunohistochemistry on paraffin embedded sections: dilute 1: 50-1: 100 in an ABC method(30 minutes at room temperature). Recommended positive control: Lung.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Hatano, Akiyama, Tamura, Hosogi, Marunaka, Caplan, Ueno, Tsukita, Asano: "Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1660-71, (2015) (PubMed).

Fonseca, Freund, Bornhäuser, Corbeil: "Polarization and migration of hematopoietic stem and progenitor cells rely on the RhoA/ROCK I pathway and an active reorganization of the microtubule network." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31661-71, (2010) (PubMed).
抗原

Ezrin (EZR)

别名

Ezrin

背景

Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. Ezrin is a cytoplasmic protein enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81

基因ID

7430

NCBI登录号

NP_001104547

UniProt

P15311

途径

Maintenance of Protein Location