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HSPG2 抗体

HSPG2 适用: 人, 小鼠, Cow, 大鼠, Wolf, Bacteria, Cod WB, IP, IHC (p), IF, IHC (fro) 宿主: 大鼠 Monoclonal A7L6 unconjugated
产品编号 ABIN114947
发货至: 中国
  • 抗原 See all HSPG2 抗体
    HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
    适用
    人, 小鼠, Cow, 大鼠, Wolf, Bacteria, Cod
    宿主
    • 19
    • 6
    • 6
    大鼠
    克隆类型
    • 20
    • 11
    单克隆
    标记
    • 21
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSPG2 antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 10
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    A7L6 recognizes domain IV of the core protein of the large Heparan Sulphate Proteoglycan or Perlecan. The reactivity is independent of the galactosaminoglycan moieties. Therefore, the epitope is not sensitive to Heparitinase treatment.
    纯化方法
    Purified
    免疫原
    High molecular mass material derived from the Engelbreth-Holm-Swarm (EHS) tumor matrix containing laminin, entactin and HSPG.
    克隆位点
    A7L6
    亚型
    IgG2a
    Top Product
    Discover our top product HSPG2 Primary Antibody
  • 应用备注
    Immunoprecipitation. Immunoblotting: 1/100-1/1000. Immunocytochemistry. Immunohistochemistry on frozen and paraffin-embedded tissues: 1/25-1/200 (withavidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Do not freeze working dilutions.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the original vial at 2-8 °C. After reconstitution store (in aliquots) at -20 °C.
  • 抗原
    HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
    别名
    HSPG2 / Perlecan (HSPG2 产品)
    别名
    HSPG antibody, PLC antibody, PRCAN antibody, SJA antibody, SJS antibody, SJS1 antibody, HSPG2 antibody, AI852380 antibody, Pcn antibody, Plc antibody, per antibody, Per antibody, heparan sulfate proteoglycan 2 antibody, perlecan (heparan sulfate proteoglycan 2) antibody, HSPG2 antibody, hspg2 antibody, Hspg2 antibody
    背景
    Proteoglycans are macromolecules consisting of a variety of core proteins with covalently attached one or several polysaccharide chains of the glycosaminoglycan type (heparan sulphate, heparin, chondroitin sulphate, dermatan sulphate or keratan sulphate). At least two forms of basement membrane heparan sulphate proteoglycan (HSPG) have been identified. One with a large core protein (> 400 kD) and one with a small core protein (30 kD). The large HSPG is probably the most abundant basement membrane proteoglycan. It is located predominantly in the lamina lucida, where it forms clustered aggregates and interacts with other basement membrane components to form the matrix. In addition, it also plays a critical role in attachment of cells to the basal membrane via integrin receptors.Synonyms: Basement membrane-specific heparan sulfate proteoglycan core protein, PLC
    基因ID
    3339
    NCBI登录号
    NP_005520
    UniProt
    P98160
    途径
    Glycosaminoglycan Metabolic Process, Lipid Metabolism
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