Thymidine Phosphorylase 抗体
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- 抗原 See all Thymidine Phosphorylase (TYMP) 抗体
- Thymidine Phosphorylase (TYMP)
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适用
- 人, 大鼠, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Thymidine Phosphorylase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody is specific to a 55 kDa protein known as Platelet-Derived Endothelial Growth Factor (PD-ECGF), similar to thymidine phosphorylase (TP). Cellular localization: Cytoplasmic, Nuclear.
- 纯化方法
- Purified
- 免疫原
- A recombinant full length human thymidine phophorylase (TP/PD-ECGF) protein.
- 克隆位点
- P-GF-44C
- 亚型
- IgG1
- Top Product
- Discover our top product TYMP Primary Antibody
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anti-Thymidine Phosphorylase (TYMP) (AA 311-482) antibody
TYMP 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1H7 unconjugated
anti-Thymidine Phosphorylase (TYMP) (AA 29-305) antibodyTYMP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Phosphorylase (TYMP) (AA 1-200) antibodyTYMP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Phosphorylase (TYMP) antibodyTYMP 适用: 人, 大鼠, 小鼠 IHC, StM 宿主: 兔 Monoclonal TYMP-2890R unconjugated Recombinant Antibody
anti-Thymidine Phosphorylase (TYMP) (N-Term) antibodyTYMP 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Phosphorylase (TYMP) (AA 1-482) antibodyTYMP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Phosphorylase (TYMP) antibodyTYMP 适用: 人, 大鼠, 小鼠 WB, IHC, IP, StM 宿主: 小鼠 Monoclonal P-GF-44C unconjugated
anti-Thymidine Phosphorylase (TYMP) antibodyTYMP 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Phosphorylase (TYMP) (AA 13-254) antibodyTYMP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Phosphorylase (TYMP) (N-Term) antibodyTYMP 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: Use a dilution of1/25-1/75 in an ABC method (30 minutes at room temperature). Western blotting: 1/50-1/100. Recommended Positive Control: Breast carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Thymidine Phosphorylase (TYMP)
- Abstract
- TYMP 产品
- 别名
- ECGF antibody, ECGF1 antibody, MEDPS1 antibody, MNGIE antibody, MTDPS1 antibody, PDECGF antibody, TP antibody, hPD-ECGF antibody, 2900072D10Rik antibody, Ecgf1 antibody, PD-ECGF antibody, Pdgfec antibody, typh antibody, thymidine phosphorylase antibody, thymidine phosphorylase DeoA antibody, AMP phosphorylase antibody, Thymidine phosphorylase antibody, TYMP antibody, Tymp antibody, deoA antibody, Dd586_0614 antibody, Kvar_4413 antibody, NMAG_RS19330 antibody, Snov_1187 antibody, Fbal_2856 antibody, Ftrac_2071 antibody, Intca_1216 antibody, ARCVE_RS10415 antibody, Sphch_4174 antibody, Sinme_3461 antibody, METOK_RS06355 antibody, Mesop_1831 antibody, typh antibody
- 背景
- Platelet - derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites. High levels of TP/PD-ECGF are observed in cancer patients. High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.Synonyms: ECGF1, Gliostatin, PD-ECGF, Platelet-derived endothelial cell growth factor, TdRPase
- 基因ID
- 1890
- NCBI登录号
- NP_001107227
- UniProt
- P19971
- 途径
- Signaling Events mediated by VEGFR1 and VEGFR2
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