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CCL7 抗体

This anti-CCL7 antibody is a 小鼠 单克隆 antibody detecting CCL7 in WB 和 EIA. Suitable for 人.
产品编号 ABIN114719
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCL7 抗体 (ABIN114719)

抗原

See all CCL7 抗体
CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

适用

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宿主

  • 42
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  • 1
小鼠

克隆类型

  • 56
  • 29
单克隆

标记

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This CCL7 antibody is un-conjugated

应用范围

  • 57
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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

542
  • 特异性

    Reactive with natural and recombinant Human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Recombinant human MCP-3 (M.W. 8.5 kDa containing 76 amino acids residues)

    亚型

    IgG2a
  • 应用备注

    ELISA: CCL7 antibody can be used as a Capture antibody in Sandwich ELISA applicationsfor Human MCP-3 Detection in combination with a monoclonal tracer/detection antibody. Suggested Capture Coating Dose: 3 μg/well. Substrate: TMB. Western Blot: An antibody concentration of 0.5-2 μg/mL will allow visualization of 0.1 μg/lane of Human MCP-3.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with Double distillated to adjust the final concentration to 1.00 mg/mL

    缓冲液

    0.01 M PBS, pH 7.2 without preservatives

    储存液

    Without preservative

    注意事项

    This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Store the antibody at 2 - 8 °C. DO NOT FREEZE!
  • 抗原

    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

    别名

    MCP3 / CCL7

    背景

    Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78 % sequence homology with MCP-1 and 58 % sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7

    基因ID

    6354

    NCBI登录号

    NP_006264

    UniProt

    P80098
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