Liver Arginase 抗体
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- 抗原 See all Liver Arginase (ARG1) 抗体
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Liver Arginase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- The Anti Human Arginase, Clone 6G3 is a Mouse monoclonal antibody against recombinant Human Arginase-liver type Arginase.
- 纯化方法
- Purified
- 免疫原
- Recombinant human liver-type aginase produced in E. coli.
- 克隆位点
- 6G3
- 亚型
- IgG1
- Top Product
- Discover our top product ARG1 Primary Antibody
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- 应用备注
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Add 0.1 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.05 M Phosphate buffer, 0.5 M NaCl, pH 7.2, None
- 储存液
- Azide free
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
- 有效期
- 6 months
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- 抗原
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- 别名
- Arginase-1 (ARG1 产品)
- 别名
- SI:zC146F4.4 (novel protein with NUDIX domain) antibody, si:ch211-146f4.3 antibody, argi1 antibody, AI antibody, AI256583 antibody, Arg-1 antibody, PGIF antibody, arginase 1 antibody, arginase antibody, Arginase-1 antibody, arginase, liver antibody, L-arginase antibody, arg1 antibody, PGTG_16455 antibody, argi1 antibody, ARG1 antibody, Arg1 antibody
- 背景
- Arginase [EC 3.5.3.1, L-arginine aminohydrolase] is an enzyme that hydrolyzes Larginine to L-ornithine and urea in the urea cycle. Two forms of arginase exists which are designed as arginase I and arginase II. Livertype arginase I is expressed primarily in the liver and to some extend in the erythrocytes. Arginase II is expressed in many extrahepatic tissues, such as brain, spinal cord, kidney, small intestine and mammary gland. Although arginase I and arginase II have similar enzyme activities, they have different pI, immunological reactivity and are encoded by different genes. Human arginase I is a 35 kDa protein circulating in blood probably as a homotrimer. Circulating liver-type arginase was clinically used as a liver specific marker which may reflect not only early occurrence of liver injury but also early termination of liver injury. The measurement of liver-type arginase is clinically applicable for monitoring conditions of patients with liver disorders or pre- and postoperative conditions of patients who received partial hepatectomy with quicker normalization in comparison with aminotransferases (ALT and AST). Recently, arginase I gene was found to be one of the most prominent among astma genes. In situ hybridization demonstrated marked staining of arginase I in submucosal inflammatory lesions and arginase activity increased in allergen challenged lungs. Finally, it was found that both arginase I was the most significantly up-regulated protein in the murine spinal cord during experimental autoimmune encephalomyelitis. The results indicated that arginase I played important roles in autoimmune inflammation in the central nervous system.Synonyms: ARG1, Liver-type arginase, Type I arginase
- 基因ID
- 383
- NCBI登录号
- NP_000036
- UniProt
- P05089
- 途径
- Cellular Response to Molecule of Bacterial Origin
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