GFAP 抗体
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北京 101111
Quick Overview for GFAP 抗体 (ABIN114688)
抗原
See all GFAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody 6F2 reacts exclusively with glial fibrillary acidic protein which is present in astrocytes in the central nervous system and Schwann cells.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Purified
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免疫原
- Glial fibrillary acidic protein from human brain.
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亚型
- IgG1
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应用备注
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Suitable for Immunoblotting and Immunohistochemistry on frozen sections andparaffin-embedded tissues. Recommended dilutions: 1/25-1/200 for Immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent, and 1/100-1/1000 forImmunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C and reconstituted at -20 °C.
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- GFAP (Glial Fibrillary Acidic Protein (GFAP))
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别名
- GFAP
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背景
- GFAP (55 kD) is selectively located in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the proliferation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer's disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in non-myelin forming Schwann cells GFAP persists into adulthood.Synonyms: Glial Fibrillary Acidic Protein
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基因ID
- 2670
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NCBI登录号
- NP_001229305
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UniProt
- P14136
抗原
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