KRT17 抗体
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北京 101111
Quick Overview for KRT17 抗体 (ABIN114619)
抗原
See all KRT17 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Clone E3 reacts with Cytokeratin 17 in basal layers of pseudo-stratified and transitional epithelia.
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交叉反应 (详细)
- Species reactivity (tested):Human, Rat.
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纯化方法
- Purified
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免疫原
- A cytoskeletal preparation from rat colon
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亚型
- IgG2b
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应用备注
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Immunoblotting (1: 100 - 1: 1000). Immunocytochemistry. Immunohistochemistry on frozen and paraffin-embedded tissues (1: 25- 1: 200 forimmunohistochemistry with avidin-biotinylated horseradish peroxidase complec (ABC) asdetection regant). Flow cytometry (1: 25-1: 200)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KRT17 (Keratin 17 (KRT17))
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别名
- Cytokeratin 17
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背景
- Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immuno-histochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK17, Cytokeratin-17, K17, KRT17, Keratin 17, Keratin type I cytoskeletal 17, Keratin-17
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分子量
- 46 kDa
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基因ID
- 3872
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NCBI登录号
- NP_000413
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UniProt
- Q04695
抗原
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